Les Paul persisted to refine the design for a solid body electric guitar, create multiple gold records, invent today’s recording techniques, be inducted into multiple halls of fame, and play his guitar until two months before he died at 94 years old in August 2009.
Antibiotics Damage Hearing Through Different Mechanisms
Understanding the multiple mechanisms behind how aminoglycoside antibiotics are able to kill hair cells may provide new potential therapeutic avenues to make these important drugs safer.
New Insights on Hearing Development in Children
This indicates an extended timeline of auditory development in children, which has exciting scientific and clinical implications.
How Blast Injuries Disrupt Brain Cell Stress Responses
The findings suggest that blast injuries cause excessive activation of PARP1, which disrupts the brain’s natural ability to manage stress and inflammation. This reduces the activity of sirtuins, which help regulate cell repair and stress responses.
Advanced Imaging Sheds Light on Inner Ear Scarring
Because of the increased network depth, upscaled input resolution, and the ability to perform well in a limited data setting, our new imaging model aided by machine learning outperformed previous state-of-the-art models predicting cochlear implant success outcomes.
Meeting Our Researchers at ARO 2025
As always we are so thrilled to meet and catch up with our funded scientists, past and present, at this important research conference.
Can Machine Learning Predict Who Will Benefit Most From Cochlear Implants?
Despite challenges, the potential of machine learning to improve cochlear implant outcomes is clear. By refining models, improving data quality, and addressing ethical concerns, we can move toward a future where CIs are more personalized and effective.
Study Maps Brain’s Ability to Comprehend Sound
New research reveals the unique patterns of gene expression in specific neurons in the brain that process the signals of sound and enable communication.
Balance in Older Mice Relies on Specific Brain Cells
This study suggests that this class of neurons may compensate for age-related loss of vestibular function to maintain balance performance in older animals.
Analysis of Six Gene Delivery Methods in the Mouse Model
By understanding which AAV serotype works best for delivering genetic instructions to specific brain cells and sharing this information in an open-access journal, researchers can design better experiments and potentially develop treatments for brain-related conditions.