Research

Advancing Research and Treatment for Ménière’s Disease

While significant challenges remain, ongoing efforts in genetic research, immunology, and clinical trials offer hope for better management and potential cures for Ménière’s disease in the future.

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Advanced Imaging Sheds Light on Inner Ear Scarring

Because of the increased network depth, upscaled input resolution, and the ability to perform well in a limited data setting, our new imaging model aided by machine learning outperformed previous state-of-the-art models predicting cochlear implant success outcomes.

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Meeting Our Researchers at ARO 2025

As always we are so thrilled to meet and catch up with our funded scientists, past and present, at this important research conference.

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Can Machine Learning Predict Who Will Benefit Most From Cochlear Implants?

Despite challenges, the potential of machine learning to improve cochlear implant outcomes is clear. By refining models, improving data quality, and addressing ethical concerns, we can move toward a future where CIs are more personalized and effective. 

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A New Tool for Targeting Only Supporting Cells in the Inner Ear

This research shows that it is possible to design gene therapies for the ear that are carefully targeted at supporting cells, an essential first step in applying targeted gene therapies to treat hearing loss in humans.

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Can a Simple Cost-Saving Method Improve Hearing Healthcare?

One cost assessment method that has been increasingly used in medical literature is called “time-driven activity-based costing.” TDABC allows for a detailed step-by-step analysis of a process and its costs, which helps identify opportunities for reducing unnecessary costs and streamlining the process. 

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Study Maps Brain’s Ability to Comprehend Sound

New research reveals the unique patterns of gene expression in specific neurons in the brain that process the signals of sound and enable communication.

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Balance in Older Mice Relies on Specific Brain Cells

This study suggests that this class of neurons may compensate for age-related loss of vestibular function to maintain balance performance in older animals.

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The Promise of Precision Medicine Through a Microneedle

Future treatments for hearing loss—including gene therapy—could come to rely on a tiny 3D-printed microneedle.

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Analysis of Six Gene Delivery Methods in the Mouse Model

By understanding which AAV serotype works best for delivering genetic instructions to specific brain cells and sharing this information in an open-access journal, researchers can design better experiments and potentially develop treatments for brain-related conditions.

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