We can now treat otoferlin-related hearing loss. In the next 10 years, we will continue to reach more groups with specific causes of hearing loss—momentum that will help accelerate the process for everyone.
A New Tool for Targeting Only Supporting Cells in the Inner Ear
This research shows that it is possible to design gene therapies for the ear that are carefully targeted at supporting cells, an essential first step in applying targeted gene therapies to treat hearing loss in humans.
The Promise of Precision Medicine Through a Microneedle
Future treatments for hearing loss—including gene therapy—could come to rely on a tiny 3D-printed microneedle.
The Wonderful World of Hearing
I’d like to share four important breakthroughs in hearing research over the past year, and how each also connects back to Hearing Health Foundation, to varying degrees. These major advances offer hope for how we might improve or restore hearing and, by extension, bring a bit more of that wonderful world into everyone’s lives.
Key Findings and Next Steps
Where do we want our hair cell regeneration research to be in three years’ time, and what will it take to get us there?
Gene Therapy for Hearing Loss: Interpreting Preliminary Clinical Trial Results
Our independent analysis of the clinical trials’ published data yields the following insights on gene therapy for hearing loss from otoferlin variants. The clinical trials provide the first validation of pharmacological treatments for hearing loss.
Seeing Friends at ARO in Anaheim
Palpable excitement was raised by reports from researchers who have recently published results of landmark gene therapy trials in young children targeting the otoferlin gene.
Recruiting for a Gene Therapy Trial
Right now we are actively recruiting volunteers with hearing loss to participate in an outpatient research study to understand the genes that cause non-syndromic autosomal dominant hearing loss (DFNA).