Our Emerging Research Grants program is the leading seed funding opportunity for early stage researchers. ERG also includes Expanded and Focused Discovery Awards, which are grant opportunities in specific topics (such as central auditory processing disorder, hyperacusis, Ménière’s disease, and tinnitus) that are open to eligible investigators at any career stage.
Are You ‘Otoaging’?
Otoaging is a new word I coined to describe both the premature aging of cochlear hair cells and synapses caused by noise, and the end result, hearing loss in old age. I was inspired by the term photoaging, used by dermatologists to describe the premature aging of the skin by sun.
Using a Computer Model to Understand the Brain’s Response to Sound
In the aging model, we explored neuronal alterations in the auditory brainstem and reproduced changes observed in aged gerbils. These results suggest that the model can help identify possible neural explanations for changes in hearing test results.
Age-Related Hearing Loss Limits Cue Use in Noise
Complexity Behind Why Hearing in Noise Gets Harder With Age
Younger and older adults improved at similar rates from lower levels of noise—meaning that both groups benefited equally from better listening conditions. But older adults needed a head start: They needed lower levels of background noise to reach the same accuracy.
Serotonin’s Dual Action in the Auditory Midbrain
Serotonin seems to quiet down excitatory neurons while boosting inhibitory ones. This differential modulation may help us to understand the role of serotonin in auditory disorders such as tinnitus and age-related hearing loss.
Hearing Loss From Diabetes: The ‘Silent’ Side Effect
Because the very small blood vessels in the inner ear can be narrowed by the presence of an increase in blood glucose, the function of the inner ear hair cells can be affected. The first symptom might be tinnitus or an inability to hear words clearly.
Virus-Delivered Therapy Reduces Sound Damage in the Mouse Ear
Our data showed that introducing the mutated nicotinic receptor into otherwise healthy ears can prevent, to some extent, permanent auditory damage caused by loud noise and accelerate hearing recovery.
Auditory Cue Use Changes With Age?
The results of our research suggest that individual differences in the ability to use auditory cues in noise may contribute to the range of communication challenges experienced by older adults.
Changes in the Brain with Age and Hearing Loss
A better understanding of how our brains process patterns with aging and hearing loss, and when neural responses are exaggerated versus diminished, can aid in developing treatments and devices to improve age- and hearing loss-related hearing difficulties.