This suggests that birds maintain a precise program for hair cell regeneration that preserves frequency-specific nerve connections, which is an important aspect of proper functional recovery.
Lucky to Be Different
What We Can Learn From the Eclipse
Understanding Pain Signals Triggered by Damage to the Inner Ear
Of relevance to hyperacusis, prior noise-induced hearing loss leads to the generation of prolonged and repetitive activity in type II neurons and surrounding tissues. This aberrant signaling may be the basis for the sensitivity to everyday sounds seen in hyperacusis.
Hearing With Humor
Surprising Role of Auditory Neurons in Learning Revealed by Study in Mice
These findings suggest that the auditory cortex may transmit significant non-auditory signals relevant for learning-related plasticity.
Tackling the Health Risks of Social Isolation
“Lacking social connection is as dangerous as smoking up to 15 cigarettes a day,” according to a U.S. Surgeon General report.
How the Brain Filters Out Tinnitus Signals in Mild Cases
As a result, increased prefrontal activity may be helpful in improving gating function (automatic filtering), a topic for future research.
Gene Therapy for Hearing Loss: Interpreting Preliminary Clinical Trial Results
Our independent analysis of the clinical trials’ published data yields the following insights on gene therapy for hearing loss from otoferlin variants. The clinical trials provide the first validation of pharmacological treatments for hearing loss.
Cochlear Organoids Reveal How Supporting Cells Differentiate Into Hair Cells
These details gleaned from this regenerative process in the mouse organoid provides insights into how mammalian supporting cells could be reprogrammed into hair cells.