Research

Protocols for Preparing Mouse Balance Organs for Research

One challenge in studying vestibular organs is their location within the bony inner ear and their small size, especially in mice, which have become an advantageous mammalian model.

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Clues to How the Auditory Cortex Controls Subcortical Circuits

Our results may provide broadly generalizable insight into how the mammalian brain dynamically processes incoming sensory information.

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Hearing Health Foundation Mourns the Passing of Neil Segil, Ph.D.

Neil Segil, Ph.D., died peacefully in his sleep on July 2 at his home in California. He had been battling pancreatic cancer and was able to spend the last couple of months at home with his family. Neil’s contributions to science, HHF’s Hearing Restoration Project, and many colleagues’ careers were invaluable.

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If Only We Could See the Noise Exposure

With a noisy holiday on the horizon (hello, fireworks!), let’s remember how too much noise poses a risk to our hearing and overall well-being, and how we should protect our hearing, for life.

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Perceptual Decision-Making for Speech Recognition in Noise

Our study indicates that perceptual decision-making is engaged for difficult word recognition conditions, and that frontal cortex activity may adjust how much information is collected to benefit word recognition task performance.

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The Enduring Legacy of Les Paul in Music and Science

Since 2014 the Les Paul Foundation has funded six Emerging Research Grants on tinnitus, deepening our understanding of its causes as well as improving diagnosis, treatment, and prevention.

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Hope for Treatments Against Hearing Loss as 10 New Genes Identified

Researchers argue that the stria vascularis, a part of the cochlea in the ear, is a new target for treatments to help people with hearing loss.

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Using Algorithms to Measure Brain Response Times to Auditory Nerve Stimulation

The proposed algorithms could provide a clue on the signal response and its shifts in the brain during the development of hyperactivity, a neural mechanism of tinnitus, and lead to an in-depth understanding of the information flow inside the auditory pathway. This will help us to better understand the mechanisms of tinnitus.

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Increasing Our Understanding of Avian Hair Cell Regeneration   

We provide evidence that in the regenerating basilar papilla, the expression of immune-related genes is tightly controlled, such that four days after damage, they are no longer expressed in newly regenerated hair cells. This is important because the JAK/STAT signaling pathway is highly potent, leading to inflammation, cytokine storms, and fibrosis.

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Explanations for Cochlear Implant Hesitancy—and What to Do About It

Despite the benefits of cochlear implantation, adoption is low. Current cochlear implant (CI) usage among adults who are indicated for them is about 5 percent. Uncertainty surrounding the outcome of cochlear implantation drives top patient concerns.

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