mouse cochlea

Hope for Treatments Against Hearing Loss as 10 New Genes Identified

Researchers argue that the stria vascularis, a part of the cochlea in the ear, is a new target for treatments to help people with hearing loss.

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The Role of Spontaneous Electrical Activity in the Developing Auditory System

Specific ion currents have been identified as major players supporting this electrical activity in developing and regenerating chick hair cells. This research details the role of small-conductance, calcium-ion-activated potassium channels (SK) in developing and regenerating chick hair cells.

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Novel Small Molecule Promotes Synaptic Regeneration In Vitro

This work furthers the development of an effective drug delivery platform for the inner ear that uses the cochlear bone as a depot for prolonged neurotrophic stimulation of spiral ganglion neurons. Our method may bypass the pitfalls of systemic administration—increased risk of side effects and insufficient levels of drug delivery—and the dangers related to opening the cochlea.

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Webinar Recap: The Present and Future of Inner Ear Hair Cell Regeneration

On July 12, Hearing Health Foundation (HHF) hosted “The Present and Future of Inner Ear Hair Cell Regeneration” on Zoom. This webinar was co-presented by 2009-2010 ERG scientist Ronna Hertzano, M.D., Ph.D. of the Hearing Restoration Project, and the consortium’s scientific director, Lisa Goodrich, Ph.D.

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How Beautiful Hearing Loss Research Can Be

Hearing Health Foundation (HHF)’s scientists study sensory cells in various species to better understand how they are damaged and how they can be regenerated to restore human hearing. Here are five of the most breathtaking images from our scientists’ labs showcasing the beauty of the hearing and balance functions.

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Study Charts Developmental Map of Inner Ear Sound Sensor in Mice

Scientists at the National Institute on Deafness and Other Communication Disorders (NIDCD), part of the National Institutes of Health, and their collaborators analyzed data from 30,000 cells from mouse cochlea, the snail-shaped structure of the inner ear. The results provide insights into the genetic programs that drive the formation of cells important for detecting sounds. The study also sheds light specifically on the underlying cause of hearing loss linked to Ehlers-Danlos syndrome and Loeys-Dietz syndrome.

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