gene expression

Combination of Four Genes May Help Regrow New Auditory Hair Cells in Mammals

Two months after treatment, we saw that some GAPS-treated guinea pigs had a statistically significant increase in new hair cell-like cells compared with controls. Future steps will be to investigate the origin as well as the function of these hair cell-like cells.

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HHF Is 65 This Year!

More funding and more time leads to more ambitious experimental plans, additional data collected, and a stronger footing for subsequent research and research funding.

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Molecular Barriers to Overcome for Hair Cell Regeneration in the Adult Mouse Cochlea

The research suggests that reprogramming with multiple transcription factors is better able to access the hair cell differentiation gene regulatory network, but that additional interventions may be necessary to produce mature and fully functional hair cells.

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Webinar Recap: The Present and Future of Inner Ear Hair Cell Regeneration

On July 12, Hearing Health Foundation (HHF) hosted “The Present and Future of Inner Ear Hair Cell Regeneration” on Zoom. This webinar was co-presented by 2009-2010 ERG scientist Ronna Hertzano, M.D., Ph.D. of the Hearing Restoration Project, and the consortium’s scientific director, Lisa Goodrich, Ph.D.

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Data Made Visual

Over the past several years, Hearing Health Foundation (HHF)’s Hearing Restoration Project (HRP) has generated a significant amount of data. Part of the challenge for HRP consortium members, as for many life scientists, comes not only from the amount of data they need to analyze but also the need to examine multi-omic datasets.

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