Manoj Kumar, Ph.D., University of Pittsburgh
Research Topic: Signaling mechanisms of auditory cortex plasticity after noise-induced hearing loss
Long-Term Goal: To identify the molecular and cellular therapeutic targets for treating and rehabilitating the impaired hearing associated with tinnitus and hyperacusis.
Published Research
Cortical zinc signaling is necessary for changes in pupil diameter that are evoked by background sounds with different contrast in mice, The Journal of Neuroscience, 2024.
Cell-type-specific plasticity of inhibitory interneurons in the rehabilitation of auditory cortex after peripheral damage, Nature Communications, 2023.
A CRE/DRE Dual Recombinase Transgenic Mouse Reveals Synaptic Zinc-Mediated Thalamocortical Neuromodulation, Science Advances, 2023.
A Genetically Encoded Far-Red Fluorescent Indicator for Imaging Synaptically Released Zn2+, Science Advances, 2023.