Kristi Hendrickson, Ph.D., University of Iowa
Research Topic: Neural correlates of semantic structure in children who are hard of hearing
Long-Term Goal: To identify key factors that influence language outcomes in children who are hard of hearing.
Published Research
Speech Sound Categories Affect Lexical Competition: Implications for Analytic Auditory Training, Journal of Speech, Language, and Hearing Research, 2024.
Inhibition of lexical representations after violated semantic predictions, Cognition, 2023.
Barriers to Equity in Pediatric Hearing Health Care: A Review of the Evidence, Perspectives of the ASHA Special Interest Groups, 2022.
The Role of Orthography and Phonology in Written Word Recognition: Evidence From Eye-Tracking in the Visual World Paradigm, Journal of Speech, Language, and Hearing Research, 2022.
School-Age Children Adapt the Dynamics of Lexical Competition in Suboptimal Listening Conditions, Child Development, 2021.
The Recognition of Whispered Speech in Real-Time, Ear & Hearing, 2021.
The profile of real-time competition in spoken and written word recognition: more similar than different, Quarterly Journal of Experimental Psychology, 2021.
Visual and haptic responses as measures of word comprehension and speed of processing in toddlers: Relative predictive utility, Journal of Experimental Child Psychology, 2020.
Cognitive processes underlying spoken word recognition during soft speech, Cognition, 2020.
NIH & Other Major Federal Funding: $1,320,178
Language outcomes, mechanisms, and trajectories in adults with and without Developmental Language Disorder, NIDCD, $573,686 awarded in 2023.
Language outcomes, mechanisms, and trajectories in adults with and without Developmental Language Disorder, NIDCD, $581,183 awarded in 2022.
Word recognition in dual language learners: The mechanisms underlying listening and reading in two languages, NICHD, $75,957 awarded in 2022.
Word recognition in dual language learners: The mechanisms underlying listening and reading in two languages, NICHD, $89,352 awarded in 2021.
Hao Luo, M.D., Ph.D., Wayne State University
Research Topic: Cochlear electrical stimulation–induced tinnitus suppression and related neural activity change in the rat inferior colliculus
Long-Term Goal: To find the underlying mechanism by which CES alters neural activity to effect changes in auditory symptoms and perceptions and to develop an optimal strategy to improve clinical trials in this area.
Published Research
Spike Analysis of the Neural Activities Across the Rats' Auditory Brain Structures, Journal of Engineering and Science in Medical Diagnostics and Therapy, 2024.
The Association between Glymphatic System and Perivascular Macrophages in Brain Waste Clearance, Diagnostics, 2024.
Contributions of Hearing Loss and Traumatic Brain Injury to Blast-Induced Cortical PV Neuron Loss and Auditory Processing Deficits, Journal of Neurotrauma, 2022.
Using Time Difference Analysis Algorithms to Measure the Response Time of Rat Auditory Cortex Neurons to Auditory Nerve Stimulation, Measurement and Control, 2022.
Brain Hemispheres Swap Dominance for Processing Semantically Meaningful Pitch, Frontiers in Human Neuroscience, 2021.
Neuroinflammation and Tinnitus, Current Topics in Behavioral Neurosciences, 2021.
Evaluating Auditory Neural Activities and Information Transfer Using Phase and Spike Train Correlation Algorithms, IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2020.
Vijaya Prakash Krishnan Muthaiah, Ph.D., University at Buffalo, the State University of New York
Research Topic: Potential of inhibition of poly ADP-ribose polymerase as a therapeutic approach in blast-induced cochlear and brain injury
Long-Term Goal: To determine the mechanisms underlying both the peripheral and central aspects of blast-induced auditory neurodegeneration; and to identify and characterize potential therapeutic targets for manifestations of blast-induced traumatic brain injury, including hearing loss, cochlear synaptopathy, tinnitus, and associated deficits.
Published Research
Aberrant Brain Triple-Network Effective Connectivity Patterns in Type 2 Diabetes Mellitus, Diabetes Therapy, 2024.
Temporal expression of brainstem neurotrophic proteins following mild traumatic brain injury, Brain Research, 2024.
Disabling tinnitus and third nerve palsy following pontine hemorrhage: Application of ICF framework, Clinical Case Reports, 2024.
Application of multimodal imaging combined with artificial intelligence in eye diseases, Frontiers in Neuroscience, 2023.
Mitochondrial Dysfunction and Apoptosis in Brain Microvascular Endothelial Cells Following Blast Traumatic Brain Injury, Cellular and Molecular Neurobiology, 2023.
Functional-structural large-scale brain networks are correlated with neurocognitive impairment in acute mild traumatic brain injury, Quantitative Imaging in Medicine and Surgery, 2023.
The Influence of Motoric Maneuvers on Cervical Vestibular Evoked Myogenic Potentials (cVEMPs), Journal of the American Academy of Audiology, 2022.
Cross-species experiments reveal widespread cochlear neural damage in normal hearing, Communications Biology, 2022.
Early disturbance of dynamic synchronization and neurovascular coupling in cognitively normal Parkinson’s disease, Journal of Cerebral Blood Flow & Metabolism, 2022.
Molecular docking analysis of glycogen phosphorylase with inhibitors from Cissampelos pareira Linn., Bioinformation, 2022.
Vestibular Cochlear Manifestations in COVID-19 Cases, Frontiers in Neurology, 2022.
Blast-induced injury responsive relative gene expression of traumatic brain injury biomarkers in human brain microvascular endothelial cells, Brain Research, 2021.
Correlation of histomorphometric changes with diffusion tensor imaging for evaluation of blast-induced auditory neurodegeneration in chinchilla, Journal of Neurotrauma, 2021.
Mass spectrometry imaging of blast overpressure induced modulation of GABA/glutamate levels in the central auditory neuraxis of Chinchilla, Experimental and Molecular Pathology, 2021.
NIH & Other Major Federal Research Funding
Behavioral evidence of tinnitus and its correlation with ABR wave metrics in chinchilla induced by blast injury. Funded by the Department of Defense, Department of the Army–Army Research Office, 2020, amount undisclosed.
William “Jason” Riggs, Au.D., The Ohio State University
Research Topic: Electrophysiological characteristics in children with auditory neuropathy spectrum disorder
Long-Term Goal: To use objective techniques to further target and investigate physiologic properties of the auditory system, which can be used to better understand the underlying lesion/impairment; and to improve clinical cochlear implant mapping strategies for children with ANSD through the information gleaned from objective electrophysiologic testing.
Published Research
Post-operative evaluation of computed tomography imaging following cochlear implantation, American Journal of Otolaryngology, 2023.
Noise-Induced Hearing Loss in the Contralateral Ear During Otologic and Neurotologic Surgeries, American Journal of Otolaryngology, 2023.
The Natural History, Clinical Outcomes, and Genotype-Phenotype Relationship of Otoferlin-Related Hearing Loss: A Systematic, Quantitative Literature Review, Human Genetics, 2023.
Assessment of Cochlear Synaptopathy by Electrocochleography to Low Frequencies in a Preclinical Model and Human Subjects, Frontiers in Neurology, 2023.
Lack of Neural Contributions to the Summating Potential in Humans with Ménière's Disease, Frontiers in Neuroscience, 2022.
Can Electrocochleography Help Preserve Hearing After Cochlear Implantation With Full Electrode Insertion?, Otology & Neurotology, 2022.
Characterizing Electrophysiological Response Properties of the Peripheral Auditory System Evoked by Phonemes in Normal and Hearing Impaired Ears, Ear & Hearing, 2022.
Neural Adaptation of the Electrically Stimulated Auditory Nerve Is Not Affected by Advanced Age in Postlingually Deafened, Middle-aged, and Elderly Adult Cochlear Implant Users, Ear & Hearing, 2022.
The Effect of Advanced Age on the Electrode-Neuron Interface in Cochlear Implant Users, Ear & Hearing, 2022.
Automated Calculation of Cochlear Implant Electrode Insertion Parameters in Clinical Cone-Beam CT, Otology & Neurotology, 2021.
Relationship Between Intraoperative Electrocochleography and Hearing Preservation, Otology & Neurotology, 2021.
The Sensitivity of the Electrically Stimulated Auditory Nerve to Amplitude Modulation Cues Declines With Advanced Age, Ear & Hearing, 2021.
Intraoperative Electrocochleography in Subjects Affected by Vestibular Schwannoma and Meniere's Disease: Comparison of Results, Ear & Hearing, 2021.
Electrocochleography and Cochlear Implantation: A Systematic Review. [Review], Otology & Neurotology, 2020.
Intraoperative Monitoring of Auditory Function During Lateral Skull Base Surgery. [Miscellaneous Article], Otology & Neurotology, 2020.
Utilizing Electrocochleography as a Microphone for Fully Implantable Cochlear Implants, Scientific Reports, 2020.
Effect of Increasing Pulse Phase Duration on Neural Responsiveness of the Electrically Stimulated Cochlear Nerve, Ear & Hearing, 2020.
Prediction of the Functional Status of the Cochlear Nerve in Individual Cochlear Implant Users Using Machine Learning and Electrophysiological Measures, Ear & Hearing, 2020.
Electrocochleography During Translabyrinthine Approach for Vestibular Schwannoma Removal, Otology & Neurotology, 2020.
Recommendations for Measuring the Electrically Evoked Compound Action Potential in Children With Cochlear Nerve Deficiency, Ear & Hearing, 2020.