Alisha Lambeth Jones, Au.D., Ph.D., Auburn University
Research topic: Evaluating central auditory processing (CAP), language, and cognition skills in adolescents born prematurely
Long-Term Goal: To identify patterns of deficits in auditory processing, language, and cognition skills for both children and adolescents with a premature birth history. Once patterns of deficits are identified, early intervention treatment as well as a rehabilitation program will be developed to either prevent or treat the deficit areas.
Published Research
Acceptable Noise Levels Determined by Traditional and Self-Assessed Methods, Journal of the American Academy of Audiology, 2021.
Prematurity and the Auditory System: Considerations for Audiologists, The Hearing Journal, 2020.
Elliott Kozin, M.D., Mass. Eye and Ear, Harvard University
Research Topic: Evaluation of hearing loss and quality of life in patients with mild traumatic brain injury
Long-Term Goal: To better diagnose and treat patients with auditory dysfunction following head injury, thereby minimizing hearing loss, tinnitus, and hyperacusis. The study has implications for a broad range of individuals, including those with isolated head injuries as well as those with repetitive head injuries, such as athletes and military personnel.
Published Research
Human otopathology in scleroderma, Laryngoscope Investigative Otolaryngology, 2023.
Design of medical tympanostomy conduits with selective fluid transport properties, Science Translational Medicine, 2023.
Educational Quality of YouTube Cholesteatoma Surgery Videos: Areas for Improvement, OTO open, 2022.
Evaluating the accuracy of speech to text applications for cochlear implant candidates during COVID-19, Cochlear Implants International, 2022.
Otopathologic and Computed Tomography Correlation of Internal Auditory Canal Diverticula in Otosclerosis, Otology & Neurotology, 2022.
Information scarcity among otolaryngology applicants: A review of the largest database of programs, Laryngoscope Investigative Otolaryngology, 2022.
Reframing Our Approach to Facial Analysis, Otolaryngology–Head & Neck Surgery, 2022.
Misestimating Misattribution of Mortality to Otolaryngology Departments in US News & World Report Rankings, Otolaryngology–Head & Neck Surgery, 2022.
Assessment of Sudden Sensorineural Hearing Loss After COVID-19 Vaccination, JAMA Otolaryngology–Head & Neck Surgery, 2022.
Factors affecting operative autonomy and performance during otolaryngology training: A multicenter trial, Laryngoscope Investigative Otolaryngology, 2022.
A Rare Complication of Chronic Otitis Media: Central Skull Base Osteomyelitis Managed With Combined Endoscopic Transmastoid and Transsphenoidal Debridement, Otology & Neurotology, 2022.
Intracochlear New Fibro-Ossification and Neuronal Degeneration Following Cochlear Implant Electrode Translocation: Long-Term Histopathological Findings in Humans, Otolaryngology–Head & Neck Surgery, 2022.
Association of Pediatric Hearing Quality and Sports Participation: A Population-Based Study, Otolaryngology–Head & Neck Surgery, 2022.
A Subset of Intracanalicular Vestibular Schwannomas Demonstrates Minimal Growth Over a 10-Year Period, Otology & Neurotology, 2022.
"Transcanal view" computed tomography reformat: Applications for transcanal endoscopic ear surgery, American Journal of Otolaryngology, 2021.
Autonomy in the Operating Room: A Multicenter Study of Gender Disparities During Surgical Training, Journal of Graduate Medical Education, 2021.
Multi-institutional Study of Otolaryngology Resident Intraoperative Experiences for Key Indicator Procedures, Otolaryngology–Head and Neck Surgery, 2021.
Implementation of Mobile Audiometry During the COVID-19 Pandemic, Otolaryngology–Head and Neck Surgery, 2021.
International Survey of Operative Practices for Otologists and Neurotologists During the COVID-19 Crisis, Otology & Neurotology, 2021.
In-Office Repair of Tympanic Membrane Perforation, Otology & Neurotology, 2021.
Posterior petrous face meningiomas presenting with Ménière's-like syndrome: a case series and review of the literature, Journal of Neurosurgery, 2021.
International Survey of Operative Practices for Otologists and Neurotologists During the COVID-19 Crisis, Otology & Neurotology, 2021.
Does stapedotomy improve high frequency conductive hearing?, Laryngoscope Investigative Otolaryngology, 2021.
In Office Repair of Tympanic Membrane Perforations, Operative Techniques in Otolaryngology–Head and Neck Surgery, 2021.
Further Research Needed to Understand Relationship Between Tubarial Glands and Eustachian Tube Dysfunction, Otolaryngology–Head and Neck Surgery, 2021.
Histopathology of the Incudomalleolar Joint in Cases of “Indeterminate” Presbycusis, Otolaryngology–Head and Neck Surgery, 2021.
A Quantitative Analysis of Social Media to Determine Trends in Brain Tumor Care and Treatment, Cureus, 2020.
Rethinking the Standard Approach to Audiometric Testing, The Hearing Journal, 2020.
Single-surgeon parotidectomy outcomes in an academic center experience during a 15-year period, Laryngoscope Investigative Otolaryngology, 2020.
Systematic Review of Endoscopic Ear Surgery Outcomes for Pediatric Cholesteatoma [Review], Otology & Neurotology, 2020.
Impact of COVID-19 on Presentation of Sudden Sensorineural Hearing Loss at a Single Institution, Otolaryngology–Head and Neck Surgery, 2020.
Labyrinthine Concussion: Historic Otopathologic Antecedents of a Challenging Diagnosis, Laryngoscope Investigative Otolaryngology, 2020.
Aerosol Dispersion During Mastoidectomy and Custom Mitigation Strategies for Otologic Surgery in the COVID-19 Era, Otolaryngology–Head and Neck Surgery, 2020.
Telemedicine Algorithm for the Management of Dizzy Patients, Otolaryngology–Head and Neck Surgery, 2020.
Demonstration and Mitigation of Aerosol and Particle Dispersion during Mastoidectomy Relevant to the COVID-19 Era, Otology & Neurotology, 2020.
A Systematic Review of Nonautologous Graft Materials Used in Human Tympanoplasty, The Laryngoscope, 2020.
Effect of Powered Air-Purifying Respirators on Speech Recognition Among Health Care Workers, Otolaryngology–Head and Neck Surgery, 2020.
Auditory Quality-of-Life Measures in Patients With Traumatic Brain Injury and Normal Pure Tone Audiometry, Otolaryngology–Head and Neck Surgery, 2020.
American Neurotology Society, American Otological Society, and American Academy of Otolaryngology – Head and Neck Foundation Guide to Enhance Otologic and Neurotologic Care During the COVID-19 Pandemic, Otology & Neurotology, 2020.
Hearing Vital Signs: Mobile Audiometry in the Emergency Department for Evaluation of Sudden Hearing Loss, Otolaryngology–Head and Neck Surgery, 2020.
Long-Term Cochlear Implantation Outcomes in Patients Following Head Injury, Laryngoscope Investigative Otolaryngology, 2020.
Telemedicine Services Provided to Medicare Beneficiaries by Otolaryngologists Between 2010 and 2018, JAMA Otolaryngology–Head & Neck Surgery, 2020.
Histopathological Changes to the Peripheral Vestibular System Following Meningitic Labyrinthitis, Laryngoscope Investigative Otolaryngology, 2020.
High-Frequency Conductive Hearing Following Total Drum Replacement Tympanoplasty, Otolaryngology–Head and Neck Surgery, 2020.
Otopathologic Analysis of Patterns of Postmeningitis Labyrinthitis Ossificans, Otolaryngology–Head and Neck Surgery, 2020.
Tracking Operative Autonomy and Performance in Otolaryngology Training Using Smartphone Technology: A Single Institution Pilot Study, Laryngoscope Investigative Otolaryngology, 2019.
Assessments of Otolaryngology Resident Operative Experiences Using Mobile Technology: A Pilot Study, Otolaryngology–Head and Neck Surgery, 2019.
Patient‐reported Auditory Handicap Measures Following Mild Traumatic Brain Injury, The Laryngoscope, 2019.
Peripheral Vestibular Organ Degeneration After Temporal Bone Fracture: A Human Otopathology Study, The Laryngoscope, 2019.
Location of Small Intracanalicular Vestibular Schwannomas Based on Magnetic Resonance Imaging, Otolaryngology–Head and Neck Surgery, 2019.
Light-Based Neuronal Activation: The Future of Cranial Nerve Stimulation, Otolaryngologic Clinics of North America, 2019.
Endoscopic-Assisted Surgical Repair of Superior Canal Dehiscence Using a Keyhole Middle Fossa Craniotomy Approach, Operative Techniques in Otolaryngology-Head and Neck Surgery, 2019.
Bilayer Graft for Incisionless In-Office Endoscopic Repair of Tympanic Membrane Perforations: A Pilot Study, OTO Open, 2019.
Transcanal Computed Tomography Views for Transcanal Endoscopic Lateral Skull Base Surgery: Pilot Cadaveric Study, Journal of Neurological Surgery Part B: Skull Base, 2019.
Human Otopathology of Cochlear Implant Drill-out Procedures, Otolaryngology–Head and Neck Surgery, 2019.
NIH & Other Major Federal Funding: $633,885
Neural Mechanisms Underlying the Auditory Phenotype of Mild Traumatic Brain Injury, NIDCD, $261,695 awarded in 2023.
Neural Mechanisms Underlying the Auditory Phenotype of Mild Traumatic Brain Injury, NIDCD, $186,095 awarded in 2022.
Neural Mechanisms Underlying the Auditory Phenotype of Mild Traumatic Brain Injury, NIDCD, $186,095 awarded in 2021.
Khaleel Razak, Ph.D., University of California, Riverside
Research Topic: Age-related hearing loss and cortical processing
Long-Term Goal: To systematically examine the optimal combination of hearing aids and behavioral and pharmacological approaches to delay or prevent the declines in complex sound processing seen in presbycusis.
Published Research
Developmental Delays in Cortical Auditory Temporal Processing in a Mouse Model of Fragile X Syndrome, Journal of Neurodevelopmental Disorders, 2023.
Baclofen-associated Neurophysiologic Target Engagement across Species in Fragile X Syndrome, Journal of Neurodevelopmental Disorders, 2022.
Nicotine reduces age-related changes in cortical neural oscillations without affecting auditory brainstem responses, Neurobiology of Aging, 2022.
Neural responses to pup calls and pup odors in California mouse fathers and virgin males, Behavioural Brain Research, 2022.
A sound-driven cortical phase-locking change in the Fmr1 KO mouse requires Fmr1 deletion in a subpopulation of brainstem neurons, Neurobiology of Disease, 2022.
Functional consequences of postnatal interventions in a mouse model of Fragile X syndrome, Neurobiology of Disease, 2021.
Increased 2-arachidonoyl-sn-glycerol levels normalize cortical responses to sound and improve behaviors in Fmr1 KO mice, Journal of Neurodevelopmental Disorders, 2021.
Age- and movement-related modulation of cortical oscillations in a mouse model of presbycusis, Hearing Research, 2020.
Deletion of Fmr1 from Forebrain Excitatory Neurons Triggers Abnormal Cellular, EEG, and Behavioral Phenotypes in the Auditory Cortex of a Mouse Model of Fragile X Syndrome, Journal of Neurodevelopmental Disorders, 2020.
Abnormal development of auditory responses in the inferior colliculus of a mouse model of Fragile X Syndrome, Journal of Neurophysiology, 2020.
Multielectrode array analysis of EEG biomarkers in a mouse model of Fragile X Syndrome, Neurobiology of Disease, 2020.
Mechanisms underlying auditory processing deficits in Fragile X syndrome, The FASEB Journal, 2020.
Acute pharmacological inhibition of matrix metalloproteinase-9 activity during development restores perineuronal net formation and normalizes auditory processing in Fmr1 KO mice, Journal of Neurochemistry 2020.
Magnesium-based biodegradable microelectrodes for neural recording, Materials Science and Engineering: C, 2020.
Beneficial effects of sound exposure on auditory cortex development in a mouse model of Fragile X Syndrome, Neurobiology of Disease, 2020.
Minocycline Treatment Reverses Sound Evoked EEG Abnormalities in a Mouse Model of Fragile X Syndrome, Frontiers in Neuroscience, 2020.
Formation of grassy TiO2 nanotube thin film by anodisation in peroxide electrolyte for Cr(VI) removal under ultraviolet radiation, Nanotechnology, 2020.
Fabrication and Characterization of Biodegradable Metal Based Microelectrodes for In Vivo Neural Recording, MRS Advances, 2019
Effects of Developmental Noise Exposure on Inhibitory Cell Densities and Perineuronal Nets in A1 and AAF of Mice, Hearing Research2019
Reduced perineuronal net expression in Fmr1 KO mice auditory cortex and amygdala is linked to impaired fear-associated memory, Neurobiology of Learning and Memory, 2019.
Developmental Changes in EEG Phenotypes in a Mouse Model of Fragile X Syndrome, Neuroscience, 2019.
Genetic reduction of MMP-9 in the Fmr1 KO mouse partially rescues prepulse inhibition of acoustic startle response, Brain Research, 2019.
Reversal of ultrasonic vocalization deficits in a mouse model of Fragile X Syndrome with minocycline treatment or genetic reduction of MMP-9, Behavioural Brain Research, 2019.
NIH & Other Major Federal Funding: $1,822,806
Using nicotine to reverse age-related auditory processing deficits, NIA, $581,628 awarded in 2023.
Using nicotine to reverse age-related auditory processing deficits, NIA, $600,705 awarded in 2022.
Using nicotine to reverse age-related auditory processing deficits, NIA, $640,473 awarded in 2021.
Joseph Toscano, Ph.D., Villanova University
Research Topic: Cortical EEG measure of speech sound encoding for hearing assessment
Long-Term Goal: To develop a clinical test for identifying auditory neuropathy and other types of hearing loss that can be used for both adults and children.
Published Research
Decoding speech sounds from neurophysiological data: Practical considerations and theoretical implications, Psychophysiology, 2023.
Effects of experience on recognition of speech produced with a face maskons, 2022.
Rethinking the McGurk effect as a perceptual illusion, Attention, Perception & Psychophysics, 2021.
Effects of face masks on speech recognition in multi-talker babble noise, PLOS One, 2021.
The time-course of speech perception revealed by temporally-sensitive neural measures, WIREs Cognitive Science, 2020
A graph-theoretic approach to identifying acoustic cues for speech sound categorization, Psychonomic Bulletin & Review, 2020.
Long-lasting gradient activation of referents during spoken language processing, Journal of Memory and Language, 2020.
Age-Related Changes in Temporal and Spectral Cue Weights in Speech, Language and Speech, 2019.
Reassessing the electrophysiological evidence for categorical perception of Mandarin lexical tone: ERP evidence from native and naïve non-native Mandarin listeners, Attention, Perception & Psychophysics, 2019.
Electrophysiological Evidence for Top-Down Lexical Influences on Early Speech Perception, Psychological Science, 2019
NIH & Other Major Federal Research Funding: $421,456
Integrating information across levels of processing during real-time spoken language comprehension, NSF, $421,456 awarded in 2020.