This paper explored the potential of the stem cell-derived inner ear organoid system for studying early mammalian placode development. The results will benefit future inner ear organoid applications, such as high-throughput drug screening and cell therapy.
USC Stem Cell Study Shows When to Quit “Yapping”
It turns out that to hear a person yapping, you need a protein called Yap. Working as part of what is known as the Yap/Tead complex, this important protein sends signals to the hearing organ to attain the correct size during embryonic development, according to a new study published in the Proceedings of the National Academy of the Sciences (PNAS) from the USC Stem Cell laboratory of Neil Segil.