Xiping Zhan, Ph.D., Howard University
Research topic: Dopaminergic activity in modulation of noise-induced tinnitus
Long-term goal: To decipher the underpinnings for tinnitus and associated mental disorders with emphasis on the dopaminergic pathways and functions in order to establish a protocol by taking advantage of psychiatric drugs, such as dopaminergic active drugs, to alleviate the symptoms caused by tinnitus and the associated distress.
Published Research
Edaravone activates the GDNF/RET neurotrophic signaling pathway and protects mRNA-induced motor neurons from iPS cells, Molecular Neurodegeneration, 2022.
Chloroquine to fight COVID-19: A consideration of mechanisms and adverse effects?, Heliyon, 2020.
Synthetic mRNAs drive highly efficient iPS cell differentiation to dopaminergic neurons, STEM CELLS Translational Medicine, 2019.
BDNF as a biomarker in diagnosis and evaluation of treatment for schizophrenia and depression, Discovery Medicine, 2018.
The effects of quinine on neurophysiological properties of dopaminergic neurons, Neurotoxicity Research, 2018.
NIH Funding: $457,000
Junctophilin-3, calcium homeostasis, and neuronal dysfunction in HDL2, NINDS, $457,000 awarded in 2020.
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