Our Strategic Research Plan
Phase I – Years 1-5 – Discovery Research
Phase I will examine which genes, or which series of genes, trigger the natural regeneration of hair cells in animals such as birds and zebrafish. This phase will also examine which genes in mammals prevent the natural regeneration of hair cells. Finally, Phase I will determine the types of cells in mammals’ ears that could serve as available targets for regeneration therapies. Read about our currently funded HRP projects.
Phase II – Years 3-8 – Pathway Validation
Phase II starts with the residual cells that remain in a mammal’s inner ear after hearing loss and uses the genes identified in Phase I to trigger hair cell regeneration.
Phase III – Years 8-10 – Develop Therapies and Treatment Options
In Phase III, the HRP Consortium will partner with a pharmaceutical or other company to develop drugs that mimic the identified genes, resulting in a regenerative therapy.