This is a story of resilience, dark humor, and the technical challenge of mixing audio when your brain processes sound through a handful of electrodes instead of thousands of hair cells.

Why is a particular gene silent in a mouse supporting cell but active in a chicken supporting cell? Is the difference epigenetic? Are regulatory regions locked down in mammals? These are the kinds of questions we can now pursue systematically.

Whether you are a casual giver or a long-time philanthropist, understanding these changes—and utilizing tools like a donor-advised fund (DAF)—can help your dollars go much further.

Using the new biosensor, we discovered that zinc signaling is directly involved in how the brain processes sound in the auditory cortex during sound processing and in the amygdala during aversive responses.