Mingqian Huang, Ph.D.

The Research

Massachusetts General Hospital

Expression and function of Mlf1, a candidate gene involved in both Pou4f3 and pRb pathways, in a zebrafish model

The proposed research is to understand the potential role of Mlf1 gene in hair cell development. Mlf1 has been implicated in the pathways controlled by two hair cell genes, Pou4f3 and pRb, both of which could give rise to deafness if mutated. Therefore dysfunction of Mlf1 may play a role in deafness.