2010 Grant Recipients Announced

2010 DRF INCREASES GRANTMAKING: 2010 GRANT RECIPIENTS ANNOUNCED

Deafness Research Foundation (DRF)'s National Hearing Health Grants Center is excited to announce that it has awarded $550,000 to 22 outstanding research scientists in the field of hearing and balance science. This year represents a 16% increase in our grantmaking.

Each year, DRF awards research grants to young investigators who are exploring new avenues of hearing and balance science. These funds will support research in the following areas: 

  • Fundamental Auditory Research -- development, genetics, molecular biology, physiology, anatomy, and regeneration biology;
  • Hearing and Balance Restoration -- infants, children and adults
    • cochlear implants/surgical therapy for otosclerosis, hair cell regeneration, hearing aids, and medical therapy;
  • Hearing Loss -- aging, noise-induced, otosclerosis, viral infection (sudden deafness), ototoxicity, temporal bone pathology, otitis media, cholesteatoma, and tumors;
  • Vestibular and Balance Disorders (dizziness and vertigo, Meniere's disease); and
  • Tinnitus (ringing in the ears) and Hyperacusis (decreased tolerance of sound).

For this year's grants selection, DRF's Council of Scientific Trustees reviewed applications from scientists at renowned research institutions around the U.S. The selected research projects received detailed peer review for scientific merit and program relevance. A complete list of the 2010 grant recipients is provided below, including recipients whose research is funded in whole or part by the DRF Centurion Clinical Research Award, the C.H.E.A.R. Endowment Award, The Burch-Safford Foundation, Inc., and The Todd M. Bader Research Grant of The Barbara Epstein Foundation, Inc.

FIRST YEAR HEARING & BALANCE RESEARCH GRANT RECIPIENTS

Ranjan Batra, Ph.D., University of Mississippi Medical Center
Organization of frequency encoding in the inferior colliculus

Fangyi Chen, Ph.D., Oregon Health & Science University
In vivo study of backward propagation of the basilar membrane vibration

Soyoun Cho, Ph.D., Oregon Health & Science University
Dynamics of exo- and endocytosis at hair cells

Zhengqing Hu, M.D., Ph.D., Wayne State University School of Medicine
Innervation of in vitro-produced hair cell by neural progenitor-derived glutamatergic neurons

Judith S. Kempfle, M.D., Massachusetts Eye and Ear lnfirmary
Influence of bone morphogenetic protein 4 and retinoic acid on differentiation of inner ear stem cells

Hongzhe Li, Ph.D., Oregon Health & Science University
Mechanisms of ototoxic synergy due to sound and aminoglycosides

Sho Ohta, M.D., Ph.D., University of Utah School of Medicine
The role of bmp signaling in regulating e-cadherin endocytosis during vestibular organ formation

Albert Park, M.D., University of Utah School of Medicine
Translational studies for antiviral treatment of cytomegalovirus induced sensorineural hearing loss

Neeliyath A. Ramakrishnan, Ph.D., Wayne State University School of Medicine
Molecular interactions of the hair-cell afferent synapse

Soledad Miranda-Rottmann, Ph.D., Howard Hughes Medical Institute, The Rockefeller University
Regulation of the efferent innervation to the mouse cochlea

Armin H. Seidl, Ph.D., Virginia Merrill Bloedel Hearing Research Center, University of Washington
Morphometrics of the mammalian low frequency sound localization circuit

Yuan Wang, Ph.D., Virginia Merrill Bloedel Hearing Research Center, University of Washington
The role of subcellular regulation of trkb in dendritic geometry of auditory brainstem neurons

Jeong-Im Woo, Ph.D., House Ear Institute
Role of vasopressin-aqp2 system in endolymph regulation of es epithelial cells

SECOND YEAR HEARING & BALANCE RESEARCH GRANT RECIPIENTS

Ronna Hertzano, M.D., Ph.D., University of Maryland School of Medicine
A new protocol for selective and efficient sorting of the auditory sensory epithelium

Olga Stakhovskaya, M.D., Ph.D., University of California, San Francisco School of Medicine
Estimating optimum insertion depth for the hifocus electrode array in individual human cochleae based on high resolution ct images

Arminda Suli, Ph.D., University of Washington School of Medicine
Assessing functional recovery after mechanosensory hair cell regeneration in the zebrafish lateral line

Ruili Xie, Ph.D., University of North Carolina at Chapel Hill School of Medicine
Synaptic transmission in the principal cells of the anteroventral cochlear nucleus during age-related hearing loss

Eunyoung Yi, Ph.D., The Johns Hopkins University School of Medicine
Dopaminergic modulation of inner hair cell afferent synaptic transmission

DRF CENTURION CLINICAL RESEARCH AWARD RECIPIENT

Craig A Buchman, M.D., University of North Carolina at Chapel Hill School of Medicine
Auditory neuropathy spectrum disorder in children

This research award is funded by the Centurions of the Deafness Research Foundation. DRF has partnered with CORE Grants Program of the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) to offer a one-year Centurion Clinical Research Award (CCRA) for clinical research in hearing and balance science.

DRF C.H.E.A.R. ENDOWMENT GRANT RECIPIENT

Frances Hannan, Ph.D., New York Medical College
1st Year DRF Grant Recipient
The role of diaphanous in the auditory cytoskeleton

The C.H.E.A.R. endowment was created to support an annual Sensory-Neural Deafness Research Grant. C.H.E.A.R. (Children Hearing Education and Research) was absorbed into DRF in 1991, and we are very proud to continue their legacy of funding research in sensory-neural deafness. 

THE BURCH-SAFFORD FOUNDATION, INC., GRANT RECIPIENT

Saima Riazuddin, Ph.D., Cincinnati Children's Hospital Medical Center
1st Year DRF Grant Recipient
Defining the role of tiucellular tight junction protein in the inner ear

This research award is funded by The Burch-Safford Foundation, Inc.

THE TODD M. BADER RESEARCH GRANT OF THE BARBARA EPSTEIN FOUNDATION, INC., RECIPIENT

Marcello Peppi, Ph.D., Massachusetts Eye and Ear lnfirmary
Molecular mechanisms of dexamethasone-mediated protection from acoustic trama

This research award is funded in part by The Todd M. Bader Research Grant of The Barbara Epstein Foundation, Inc.

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Deafness Research Foundation is the leading national source of private funding for research in hearing and balance science. Research made possible by DRF grants has resulted in dramatic innovations that have increased options for those living with hearing and balance disorders, as well as protected those at risk. Since our inception in 1958, we have awarded over $26 million through more than 2,000 scientific research grants to researchers who are dedicated to exploring new avenues of hearing and balance science. With the potential of hearing restoration through regeneration biology, the scope of DRF-funded research has expanded enormously. Since 1972, DRF has funded close to 40 research grants that have been instrumental in the development, evaluation and improvement of cochlear implants. Over 188,000 implant procedures have been completed worldwide with beneficial results, particularly when the procedure is undertaken in infants. DRF also publishes the award-winning Hearing Health Magazine.

Contact: 
Trisha Donaldson
212-328-9483
tdonaldson@drf.org

Deafness Research Foundation
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New York, NY 10022-4503
Voice (212) 328-9480
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www.drf.org

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